• ProductCode:HOR-266
• Synonyms/ProductAlternateNames:PTH(7-34)Human,PTH/PTHrPreceptorantagoNIST,PTHrPanalog,PTHR,MGC138426,MGC138452.

• Introduction:Polypeptidehormonessecretedbytheparathyroidglands,whichpromotereleaseofcalciumfrombonetoextracellularfluidbyactivatingosteoblastsandinhibitingosteoclasts,indirectlypromoteincreasedintestinalabsorptionofcalcium,andpromoterenaltubularreabsorptionofcalciumandincreasedrenalexcretionofphosphates.Itisamajorregulatorofbonemetabolism.Secretionofparathyroidhormoneincreaseswhenthelevelofcalciumintheextracellularfluidislow.Itsactionisopposedbycalcitonin.PTH(7-34),whichisaPTH/PTHrPreceptorantagonist,canstimulatehairgrowthandepidermalproliferationinmice.Description:ParathyroidHormoneHumanRecombinantproducedinE.Coliisasingle,non-glycosylated,polypeptidechaincontaining28aminoacidsandhavingamolecularmassof3380Dalton.ThePTHispurifiedbyproprietarychromatographictechniques.PhysicalAppearance:SterileFilteredWhitelyophilized(freeze-dried)powder.Formulation:Theprotein(1mg/ml)waslyophilizedafterextensivedialysesagainst20mMPBSpH-7.0and150mMNaCl.Solubility:ItisrecommendedtoreconstitutethelyophilizedPTHinsterile18MΩ-cmH2Onotlessthan100µg/ml,whichcanthenbefurtherdilutedtootheraqueoussolutions.StABIlity:LyophilizedParathyrinalthoughstableatroomtemperaturefor3weeks,shouldbestoreddesiccatedbelow-18°C.UponreconstitutionPTHshouldbestoredat4°Cbetween2-7daysandforfutureusebelow-18°C.Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).Pleasepreventfreeze-thawcycles.Purity:Greaterthan97.0%asdeterminedby:(a)AnalysisbyRP-HPLC.(b)AnalysisbySDS-PAGE.BIOLOGicalActivity:TheactivitycalculatedbyUMR106cell/cAMPmethodcorrespondingtoaspecificactivityof10,000Units/mg.ForLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.

• Origin:E.coli.
• StorageConditions:-20°C
• One-LetterCode:
  LMHNLGKHLNSMERVEWLRKKLQDVHNF

Peptides致力研究多肽,多肽底物,自1983年以来Peptides生产和销售多种高纯度生物活性肽,生物活性肽(Bioactive Peptides ，BAP)是对生物机体的生命活动有益或是具有生理作用的肽类化合物，是一类相对分子质量小于6000Da ， 具有多种生物学功能的多肽。生物活性肽具有多种人体代谢和生理调节功能，易消化吸收，有促进免疫、激素调节、抗菌、抗病毒、降血压、降血脂等作用，是当前国际食品界最热门的研究课题和极具发展前景的功能因子。